Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSH | P09668 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7896186 | 0.79 | TSHR (0.40) | TSHRNPC1RAB9AHSD17B10NPSR1 | |
| SCHEMBL6826673 | 0.75 | TSHR (0.53) | TSHRNPC1RAB9AALPIPKM | |
| SCHEMBL1838248 | 0.75 | SLC6A2 (0.54) | TSHRNPC1RAB9AALPIPKM | |
| SCHEMBL9813241 | 0.74 | ESR1 (0.44) | HSD17B10KMT2AKDM4ECYP2C9 | |
| SCHEMBL3505882 | 0.73 | ALDH1A1 (0.52) | TSHRNPC1RAB9AALPIPKM | |
| SCHEMBL5617244 | 0.73 | ALDH1A1 (0.52) | TSHRNPC1RAB9AALPIPKM | |
| SCHEMBL9028692 | 0.73 | ALDH1A1 (0.52) | TSHRNPC1RAB9AALPIPKM | |
| SCHEMBL9800577 | 0.73 | HPGD (0.52) | TSHRNPC1RAB9AHSD17B10NPSR1 | |
| SCHEMBL9506391 | 0.72 | CTSK (0.55) | TSHRNPC1RAB9ACTSKCTSL | |
| SCHEMBL1811694 | 0.72 | SLC6A2 (0.50) | TSHRNPC1RAB9AALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6183934-B1 | FOE USE IN FORMATION OF PATTERN OF INSULATION FILM, PASSIVATION FILM, .ALPHA.-RAY SHIELDING FILM, OPTICAL WAVEGUIDE | KABUSHIKI KAISHA TOSHIBA (JP) | 2001-02-06 | — | — | US | disclosed |