Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 5/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.44 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.44 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.37 |
| ▸ | PRKDC | P78527 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | AGER | Q15109 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7904622 | 0.92 | HRH3 (0.39) | PIK3CBPIK3CAPIK3CDPIK3R1SUV39H2 | |
| SCHEMBL7902674 | 0.91 | HRH3 (0.40) | PIK3CBPIK3CAPIK3CDPIK3R1SUV39H2 | |
| SCHEMBL7896551 | 0.89 | CNR2 (0.36) | PIK3CBPIK3CAPIK3CDPIK3R1CNR2 | |
| SCHEMBL7905274 | 0.87 | HRH3 (0.41) | PIK3CBPIK3CAPIK3CDPIK3R1KDM4E | |
| SCHEMBL7896433 | 0.85 | POLB (0.38) | SUV39H2TSHRNPSR1KDM4ELMNA | |
| SCHEMBL7904672 | 0.84 | HTR1B (0.39) | KDM4EHRH3HTR1B | |
| SCHEMBL7908545 | 0.84 | PRKDC (0.39) | PIK3CBPIK3CAPIK3CDPIK3R1PRKDC | |
| SCHEMBL7904007 | 0.83 | USP2 (0.40) | KDM4EMEN1LMNAKMT2ATDP1 | |
| SCHEMBL7896515 | 0.82 | HTR1B (0.38) | KDM4EHRH3HTR1B | |
| SCHEMBL7896441 | 0.81 | HTR1B (0.37) | KDM4EHRH3HTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191152-B1 | CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | EGIS GYÓGYSZERGYAR RT. (HU) | 2001-02-20 | — | — | US | disclosed |