Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 5/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | STAT6 | P42226 | 1/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.41 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.41 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | YES1 | P07947 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL789889 | 0.90 | RAB9A (0.48) | RAB9AKDRPIK3CAPTGDRAPP | |
| SCHEMBL790416 | 0.87 | MRGPRX4 (0.50) | RAB9AKDRPIK3CAPTGDRAPP | |
| SCHEMBL790392 | 0.84 | KDR (0.48) | RAB9AKDRLMNA | |
| SCHEMBL789915 | 0.83 | RAB9A (0.50) | RAB9AKDRLMNA | |
| SCHEMBL790646 | 0.83 | KDR (0.47) | RAB9AKDRSTAT6LMNA | |
| SCHEMBL790093 | 0.81 | SMN1; SMN2 (0.48) | RAB9AKDRPIK3CASTAT6LMNA | |
| SCHEMBL791145 | 0.79 | KDR (0.46) | RAB9AKDRPIK3CASTAT6CLK1 | |
| SCHEMBL791124 | 0.78 | APP (0.46) | RAB9APTGDRAPPACP1DYRK1A | |
| SCHEMBL790621 | 0.77 | KDR (0.46) | RAB9AKDRSTAT6CLK1DYRK1A | |
| SCHEMBL789696 | 0.77 | JAK2 (0.48) | RAB9APIK3CAPI4KAPIK3CGJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |