Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.37 |
| ▸ | CTSL | P07711 | 6/20 | 0.35 |
| ▸ | CTSB | P07858 | 6/20 | 0.35 |
| ▸ | CTSH | P09668 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7910227 | 0.84 | CTSK (0.38) | CTSKCTSLCTSBCTSHKMT2A | |
| SCHEMBL7910234 | 0.84 | CTSK (0.38) | CTSKCTSLCTSBCTSHKMT2A | |
| SCHEMBL21402585 | 0.79 | CTSK (0.40) | CTSKCTSLCTSBCTSH | |
| SCHEMBL6662787 | 0.77 | SHBG (0.41) | ALDH1A1KMT2A | |
| SCHEMBL6145227 | 0.77 | SHBG (0.41) | ALDH1A1KMT2A | |
| Methacrylic Acid SCHEMBL7162656 | 0.75 | CTSK (0.39) | CTSKCTSLCTSBCTSH | |
| SCHEMBL7907019 | 0.75 | HSD17B10 (0.45) | ALDH1A1KMT2A | |
| SCHEMBL1105462 | 0.75 | SHBG (0.37) | ALDH1A1KMT2A | |
| SCHEMBL21409652 | 0.75 | SHBG (0.37) | ALDH1A1KMT2A | |
| SCHEMBL1829740 | 0.74 | TDP1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204293-B1 | INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH | UNIVERSITY OF PITTSBURGH | 2001-03-20 | — | — | US | disclosed |