SCHEMBL789800

SCHEMBL789800

CCC(C)c1ccc2sc3c(-c4ccc5[nH]c6ccc(-c7cc(C(C)CC)cc8c7sc7ccc(C(C)CC)cc78)cc6c5c4)cc(C(C)CC)cc3c2c1

nearest known ligand 0.32

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 3/20 0.32
PIM2 Q9P1W9 3/20 0.32
SCN10A Q9Y5Y9 1/20 0.31
USP2 O75604 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
PKM P14618 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31
MCL1 Q07820 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL789807 0.85 KIF11 (0.39) PIM1PIM2ALDH1A1GAA
SCHEMBL10227108 0.80 KIF11 (0.50) PIM1PIM2ALDH1A1HPGDHSD17B10
SCHEMBL4549314 0.78 MCL1 (0.33) PIM1PIM2ALDH1A1MCL1
SCHEMBL21677455 0.77 GAA (0.46) SCN10AUSP2ALDH1A1GAAPKM
SCHEMBL8281206 0.76 NPC1 (0.38) USP2ALDH1A1GAAHPGDALOX15
SCHEMBL15746946 0.75 ALDH1A1 (0.31) SCN10AUSP2ALDH1A1GAAPKM
SCHEMBL889804 0.73 HPGD (0.41) ALDH1A1HPGDHSD17B10MCL1
SCHEMBL788687 0.73 KIF11 (0.41) PIM1PIM2ALDH1A1GAAHPGD
SCHEMBL9603912 0.73 NPC1 (0.40) ALDH1A1GAAHPGDHSD17B10
SCHEMBL10227371 0.72 RAB9A (0.35) PIM1PIM2ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9450188-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-09-20 US disclosed
US-20140145175-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-05-29 US disclosed
US-8642782-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-02-04 US disclosed
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SLC39A3, SULT1A1, NUTF2 PIM1 3603/4885PIM2 3428/4885SCN10A 4216/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.