SCHEMBL789807

SCHEMBL789807

CC(C)c1ccc2sc3c(-c4ccc5[nH]c6ccc(-c7cc(C(C)C)cc8c7sc7ccc(C(C)C)cc78)cc6c5c4)cc(C(C)C)cc3c2c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.39
PIM1 P11309 2/20 0.39
PIM2 Q9P1W9 2/20 0.39
KDM4E B2RXH2 2/20 0.35
GAA P10253 1/20 0.35
TLR9 Q9NR96 4/20 0.33
TLR8 Q9NR97 4/20 0.33
TLR7 Q9NYK1 4/20 0.33
MAPT P10636 3/20 0.32
HTT P42858 2/20 0.32
ALDH1A1 P00352 1/20 0.32
HTR1D P28221 2/20 0.32
LMNA P02545 2/20 0.32
UBE2N P61088 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
METAP2 P50579 1/20 0.32
HTR2A P28223 1/20 0.31
HTR1B P28222 1/20 0.31
CSF1R P07333 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10227108 0.94 KIF11 (0.50) KIF11PIM1PIM2KDM4EMAPT
SCHEMBL789800 0.85 PIM1 (0.32) PIM1PIM2GAAALDH1A1
SCHEMBL10225916 0.81 ALOX5 (0.52) KIF11PIM1PIM2KDM4EGAA
SCHEMBL788687 0.77 KIF11 (0.41) KIF11PIM1PIM2KDM4EGAA
SCHEMBL4549313 0.76 PIM1 (0.35) KIF11PIM1PIM2KDM4EMAPT
SCHEMBL10227371 0.76 RAB9A (0.35) KIF11PIM1PIM2KDM4EALDH1A1
SCHEMBL21376875 0.74 KIF11 (0.62) KIF11KDM4EGAAMAPTHTT
SCHEMBL8281342 0.74 RAB9A (0.35) PIM1PIM2KDM4EGAAMAPT
SCHEMBL788550 0.74 LIMK1 (0.43) PIM1PIM2MAPT
SCHEMBL786979 0.74 LIMK1 (0.43) PIM1PIM2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9450188-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-09-20 US disclosed
US-20140145175-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-05-29 US disclosed
US-8642782-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-02-04 US disclosed
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SLC39A3, SULT1A1, NUTF2 KIF11 1085/4885PIM1 3603/4885PIM2 3428/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.