Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 7/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7898154 | 0.78 | HPGD (0.38) | NR3C1CNR2 | |
| SCHEMBL692774 | 0.76 | NR3C1 (0.44) | NR3C1PRMT6KDM1ACA2PTGS1 | |
| SCHEMBL3507875 | 0.70 | CA2 (0.54) | NR3C1PRMT6KDM1ACA2PTGS1 | |
| SCHEMBL10299432 | 0.68 | NR3C1 (0.43) | NR3C1PTGS1PTGS2NR1H2NR1H3 | |
| SCHEMBL19567186 | 0.67 | PTGS1 (0.63) | PRMT6KDM1ACA2PTGS1PTGS2 | |
| Trifluoromethanesulfonic Acid SCHEMBL6668114 | 0.66 | CA2 (0.49) | NR3C1PRMT6KDM1ACA2PTGS1 | |
| SCHEMBL10894219 | 0.66 | NR3C1 (0.87) | NR3C1 | |
| SCHEMBL20782066 | 0.65 | CA2 (0.54) | PRMT6KDM1ACA2PTGS1PTGS2 | |
| SCHEMBL9571373 | 0.65 | CA2 (0.56) | NR3C1PRMT6KDM1ACA2PTGS1 | |
| SCHEMBL7715239 | 0.64 | LIMK2 (0.43) | NR3C1PRMT6CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010123822-A1 | COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING PYRIDAZINE SULFONAMIDE DERIVATIVES | INSTITUTE FOR ONEWORLD HEALTH (US) | 2010-10-28 | — | — | WO | disclosed |