Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.46 |
| ▸ | DRD4 | P21917 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL427358 | 0.79 | DGAT1 (0.50) | DGAT1HTR2AHTR2CHTR2BDRD4 | |
| SCHEMBL424464 | 0.73 | ALDH1A1 (0.51) | MAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL427640 | 0.71 | KMT2A (0.43) | DGAT1 | |
| SCHEMBL1066467 | 0.69 | HTR2A (0.72) | HTR2AHTR2CHTR2BDRD4MAPT | |
| SCHEMBL6794331 | 0.69 | DRD4 (0.79) | HTR2AHTR2CHTR2BDRD4L3MBTL1 | |
| SCHEMBL424466 | 0.69 | FAAH (0.55) | MAPK1SMN1; SMN2 | |
| SCHEMBL7459360 | 0.68 | HTR2A (0.71) | HTR2AHTR2CHTR2BDRD4MAPT | |
| Hydrochloric Acid SCHEMBL4653252 | 0.68 | HTR2A (0.71) | HTR2AHTR2CHTR2BDRD4MAPT | |
| SCHEMBL12341280 | 0.68 | HDAC1 (0.81) | HTR2AHTR2CHTR2BDRD4MAPT | |
| SCHEMBL9407904 | 0.68 | HDAC4 (0.72) | HTR2AHTR2CHTR2BDRD4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010074588-A2 | PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & Cª, S.A. (PT) | 2010-07-01 | — | — | WO | disclosed |