Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5207224 | 0.86 | FOLH1 (0.46) | CA2CA1FOLH1LCKPTGS2 | |
| SCHEMBL7263059 | 0.86 | CA2 (0.50) | CA2CA12CA1CA7CA9 | |
| Hydrochloric Acid SCHEMBL7262922 | 0.85 | CA2 (0.49) | CA2CA12CA1CA7CA9 | |
| SCHEMBL7433937 | 0.83 | KDM6B (0.57) | CA2CA1MAPTFOLH1LCK | |
| SCHEMBL22364281 | 0.83 | KDM6B (0.57) | CA2CA1MAPTFOLH1LCK | |
| SCHEMBL29700186 | 0.83 | KDM6B (0.57) | CA2CA1MAPTFOLH1LCK | |
| SCHEMBL8080032 | 0.79 | MAPT (0.64) | CA2CA12CA1CA7CA9 | |
| SCHEMBL646876 | 0.78 | CA12 (0.65) | CA2CA12CA1CA7CA9 | |
| SCHEMBL1287829 | 0.75 | FOLH1 (0.61) | FOLH1MMEACE | |
| SCHEMBL547121 | 0.75 | FOLH1 (0.61) | FOLH1MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6319702-B1 | NUCLEOTIDE SEQUENCS CODING AN ENZYMATIC POLYPEPTIDE AND CELL TARGETING COMPOUND; FOR USE IN TREATMENT OF CANCER | GLAXO WELLCOME, INC. | 2001-11-20 | — | — | US | disclosed |