Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 4/20 | 0.41 |
| ▸ | P2RX2 | Q9UBL9 | 4/20 | 0.41 |
| ▸ | CDK1 | P06493 | 6/20 | 0.39 |
| ▸ | KDR | P35968 | 4/20 | 0.39 |
| ▸ | CDK2 | P24941 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CDK4 | P11802 | 2/20 | 0.39 |
| ▸ | CDK7 | P50613 | 2/20 | 0.39 |
| ▸ | CDK9 | P50750 | 2/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | CCNH | P51946 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.39 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.37 |
| ▸ | SYK | P43405 | 3/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2790314 | 1.00 | P2RX3 (0.41) | P2RX3P2RX2CDK1KDRCDK2 | |
| SCHEMBL2789226 | 1.00 | P2RX3 (0.41) | P2RX3P2RX2CDK1KDRCDK2 | |
| SCHEMBL24103625 | 0.82 | APLNR (0.39) | P2RX3P2RX2CDK1KDRCDK2 | |
| SCHEMBL29751802 | 0.82 | APLNR (0.39) | P2RX3P2RX2CDK1KDRCDK2 | |
| SCHEMBL29751819 | 0.81 | MAPK1 (0.40) | P2RX3P2RX2CDK1KDRCDK2 | |
| SCHEMBL25950534 | 0.79 | KCNH3 (0.36) | P2RX3P2RX2CDK1KDRCDK2 | |
| SCHEMBL9602997 | 0.78 | KCNH3 (0.43) | CDK1CDK2KCNH3IDH1MAPK1 | |
| SCHEMBL20341671 | 0.77 | L3MBTL1 (0.40) | KDRCDK4CDK7CDK9CCND1 | |
| SCHEMBL6102920 | 0.77 | KDM4E (0.48) | IDH1FYN | |
| SCHEMBL7893408 | 0.77 | HCAR3 (0.46) | CDK1KDRCDK2CA2CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813293-A | Urea derivatives useful for the treatment of cancer | 蝎子疗法股份有限公司 | 2024-04-02 | — | — | CN | disclosed |
| EP-4334298-A1 | UREA DERIVATIVES WHICH CAN BE USED TO TREAT CANCER | Scorpion Therapeutics, Inc. (US) | 2024-03-13 | — | — | EP | disclosed |
| WO-2022265993-A1 | UREA DERIVATIVES WHICH CAN BE USED TO TREAT CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-12-22 | — | — | WO | disclosed |
| WO-2022265993-A1 | UREA DERIVATIVES WHICH CAN BE USED TO TREAT CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-12-22 | — | — | WO | disclosed |
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |