Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.72 |
| ▸ | RAB9A | P51151 | 5/20 | 0.72 |
| ▸ | NPC1 | O15118 | 4/20 | 0.72 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | KDM1A | O60341 | 2/20 | 0.59 |
| ▸ | MAOA | P21397 | 2/20 | 0.59 |
| ▸ | DRD4 | P21917 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | IKBKB | O14920 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6407827 | 0.89 | KDM1A (0.72) | SMN1; SMN2RAB9ANPC1TAAR1ALDH1A1 | |
| SCHEMBL6962971 | 0.84 | SMN1; SMN2 (0.89) | SMN1; SMN2RAB9ANPC1TAAR1ALDH1A1 | |
| SCHEMBL11024162 | 0.84 | RAB9A (1.00) | SMN1; SMN2RAB9ANPC1TAAR1ALDH1A1 | |
| SCHEMBL13202035 | 0.84 | HDAC2 (0.65) | SMN1; SMN2RAB9ANPC1MAPTMEN1 | |
| SCHEMBL4153362 | 0.82 | NPC1 (0.69) | SMN1; SMN2RAB9ANPC1ALDH1A1LMNA | |
| SCHEMBL2412199 | 0.82 | HDAC1 (0.75) | RAB9ANPC1 | |
| SCHEMBL11641490 | 0.81 | NR1H4 (0.59) | RAB9ANPC1 | |
| SCHEMBL4316186 | 0.78 | RAB9A (0.66) | SMN1; SMN2RAB9ANPC1TAAR1ALDH1A1 | |
| SCHEMBL4067332 | 0.78 | PKM (0.82) | SMN1; SMN2RAB9ANPC1TAAR1ALDH1A1 | |
| SCHEMBL7899407 | 0.78 | SMN1; SMN2 (0.61) | SMN1; SMN2RAB9ANPC1TAAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1602368-A2 | Cdc25 phosphatase inhibitors | Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) (FR) | 2005-12-07 | — | — | EP | disclosed |