Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 2/20 | 0.52 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.44 |
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.42 |
| ▸ | EDNRB | P24530 | 1/20 | 0.40 |
| ▸ | EDNRA | P25101 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3115744 | 0.87 | PIK3CD (0.57) | PIK3CGPIK3CAPIK3CDPIK3CB | |
| SCHEMBL29555684 | 0.87 | PIK3CD (0.57) | PIK3CGPIK3CAPIK3CDPIK3CB | |
| SCHEMBL791191 | 0.86 | PDGFRB (0.44) | PIK3CGALPLPIK3CASLC40A1PDGFRB | |
| SCHEMBL29556839 | 0.85 | ALPL (0.56) | PIK3CGALPLPIK3CASLC40A1PDGFRB | |
| SCHEMBL790824 | 0.85 | ALPL (0.56) | PIK3CGALPLPIK3CASLC40A1PDGFRB | |
| SCHEMBL790432 | 0.83 | PIK3CA (0.45) | PIK3CGALPLPIK3CASLC40A1PDGFRB | |
| SCHEMBL789981 | 0.83 | ALPL (0.48) | PIK3CGALPLPIK3CASLC40A1PDGFRB | |
| SCHEMBL791429 | 0.82 | ALPL (0.47) | PIK3CGALPLPIK3CASLC40A1PDGFRB | |
| SCHEMBL3514914 | 0.82 | CA1 (0.40) | ALPLPIK3CAPDGFRBKDR | |
| SCHEMBL19297776 | 0.81 | CA1 (0.52) | ALPLPDGFRBKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |