Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.44 |
| ▸ | SDCBP | O00560 | 5/20 | 0.44 |
| ▸ | SDC2 | P34741 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7257431 | 0.88 | THRB (0.46) | THRBSDCBPSDC2MAPTALOX15 | |
| SCHEMBL6446130 | 0.79 | TNF (0.46) | THRBMAPTALOX15SMN1; SMN2LMNA | |
| SCHEMBL6450587 | 0.79 | TNF (0.46) | THRBMAPTALOX15SMN1; SMN2LMNA | |
| SCHEMBL7257350 | 0.73 | TP53 (0.43) | MEN1KMT2APOLB | |
| SCHEMBL7976084 | 0.69 | LMNA (0.44) | THRBMAPTALOX15LMNA | |
| SCHEMBL9087773 | 0.69 | NR1H2 (0.39) | THRBMAPTALOX15SMN1; SMN2MEN1 | |
| SCHEMBL6447529 | 0.68 | DHFR (0.52) | MAPTALOX15SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6447536 | 0.68 | DHFR (0.52) | MAPTALOX15SMN1; SMN2MEN1KMT2A | |
| SCHEMBL23877050 | 0.67 | NR1H2 (0.39) | THRBMAPTALOX15SMN1; SMN2LMNA | |
| SCHEMBL3797261 | 0.66 | TNF (0.58) | MAPTALOX15MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6319702-B1 | NUCLEOTIDE SEQUENCS CODING AN ENZYMATIC POLYPEPTIDE AND CELL TARGETING COMPOUND; FOR USE IN TREATMENT OF CANCER | GLAXO WELLCOME, INC. | 2001-11-20 | — | — | US | disclosed |