Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACA | Q13085 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | GPR139 | Q6DWJ6 | 5/20 | 0.52 |
| ▸ | PRCP | P42785 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ACACB | O00763 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7681216 | 0.90 | MEN1 (0.59) | ACACAMEN1KMT2AGPR139PRCP | |
| SCHEMBL7677571 | 0.90 | MEN1 (0.59) | ACACAMEN1KMT2AGPR139PRCP | |
| SCHEMBL8949273 | 0.90 | SMN1; SMN2 (0.53) | MEN1KMT2AGPR139PRCPSMN1; SMN2 | |
| SCHEMBL8445815 | 0.86 | GPR139 (0.55) | ACACAMEN1KMT2AGPR139PRCP | |
| SCHEMBL15200212 | 0.85 | ACACA (0.57) | ACACAGPR139HPGDMAPTCNR1 | |
| SCHEMBL12768105 | 0.84 | PRCP (0.54) | ACACAMEN1KMT2APRCPGAA | |
| SCHEMBL7897298 | 0.83 | SMN1; SMN2 (0.69) | MEN1KMT2AGPR139PRCPSMN1; SMN2 | |
| SCHEMBL16975095 | 0.83 | MAPT (0.71) | ACACAMEN1KMT2AGPR139GAA | |
| SCHEMBL18241727 | 0.83 | MAPT (0.71) | ACACAMEN1KMT2AGPR139GAA | |
| SCHEMBL23122290 | 0.81 | GPR139 (0.54) | MEN1KMT2AGPR139PRCPSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3452453-B1 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | CALICO LIFE SCIENCES LLC (US) | 2022-04-13 | — | — | EP | disclosed |
| US-8377639-B2 | Compounds for modulating RNA binding proteins and uses therefor | UNIVERSITY OF MASSACHUSETTS (US) | 2013-02-19 | — | — | US | disclosed |
| US-20110065704-A1 | COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-03-17 | — | — | US | disclosed |
| US-6187582-B1 | REACTING RACEMIC AMINE AND ESTER IN PRESENCE OF LIPASE FROM CANDIDA ANTARCTICA AND DILUENT, SEPARATING MIXTURE OF (S)-AMINE, SEPARATING THE ACYLATED (R)-AMINE, THEN OPTIONALLY DEACYLATING THE (R)-AMINE BY TREATMENT WITH AN ACID OR BASE | BAYER AKTIENGESELLSCHAFT (DE) | 2001-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065704-A1 | COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR | TIA1, ZFP3, RBM3 | ACACA 3984/4885MEN1 1444/4885KMT2A 3013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.