Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | GPR139 | Q6DWJ6 | 3/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | PRCP | P42785 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ACACB | O00763 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ACACA | Q13085 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7681216 | 1.00 | MEN1 (0.59) | MEN1KMT2AHPGDALDH1A1GPR139 | |
| SCHEMBL7900323 | 0.90 | ACACA (0.56) | MEN1KMT2AHPGDALDH1A1GPR139 | |
| SCHEMBL27820665 | 0.84 | HTT (0.63) | HPGDALDH1A1CNR2LMNAACACB | |
| SCHEMBL8949273 | 0.84 | SMN1; SMN2 (0.53) | MEN1KMT2AHPGDALDH1A1GPR139 | |
| SCHEMBL27293522 | 0.84 | KMT2A (0.47) | MEN1KMT2AHPGDALDH1A1GPR139 | |
| SCHEMBL8445815 | 0.83 | GPR139 (0.55) | MEN1KMT2AHPGDALDH1A1GPR139 | |
| SCHEMBL7897298 | 0.80 | SMN1; SMN2 (0.69) | MEN1KMT2AHPGDALDH1A1GPR139 | |
| SCHEMBL16714801 | 0.80 | ALDH1A1 (0.58) | MEN1KMT2AHPGDALDH1A1CNR2 | |
| SCHEMBL23122290 | 0.79 | GPR139 (0.54) | MEN1KMT2AHPGDALDH1A1GPR139 | |
| SCHEMBL7932227 | 0.79 | GPR139 (0.54) | MEN1KMT2AHPGDALDH1A1GPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6500986-B1 | RACEMIZATION OF OPTICALLY ACTIVE AMIDES; CONVERSION TO AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-12-31 | — | — | US | claimed |
| EP-0757981-B1 | Process for the preparation of racemic amino derivatives | BAYER AG (DE) | 2000-02-16 | — | — | EP | claimed |
| US-6500986-B1 | RACEMIZATION OF OPTICALLY ACTIVE AMIDES; CONVERSION TO AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-12-31 | — | — | US | disclosed |
| EP-0757981-B1 | Process for the preparation of racemic amino derivatives | BAYER AG (DE) | 2000-02-16 | — | — | EP | disclosed |
| EP-0757981-A1 | Process for the preparation of racemic amino derivatives | BAYER AG (DE) | 1997-02-12 | — | — | EP | disclosed |