Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | ACP3 | P15309 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7900717 | 1.00 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1ESR1HPGDMEN1 | |
| SCHEMBL30487114 | 0.78 | HSD17B10 (0.46) | ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL13711952 | 0.77 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1ESR1HPGDMEN1 | |
| SCHEMBL14023438 | 0.71 | ESR1 (0.39) | ALDH1A1L3MBTL1ESR1HPGDMEN1 | |
| SCHEMBL20150130 | 0.69 | GABRA1 (0.43) | ALDH1A1L3MBTL1HPGDKMT2A | |
| SCHEMBL8861265 | 0.65 | GABRA1 (0.44) | ALDH1A1L3MBTL1HPGDKMT2A | |
| SCHEMBL15106965 | 0.65 | HPGD (0.58) | ALDH1A1HPGDMEN1HTTKMT2A | |
| SCHEMBL23707031 | 0.64 | NPSR1 (0.45) | ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL21039014 | 0.64 | TDP1 (0.40) | ALDH1A1L3MBTL1HPGDMEN1HTT | |
| SCHEMBL3787042 | 0.64 | ESR1 (0.48) | ALDH1A1L3MBTL1ESR1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10835895-B2 | Compound and synthesis method therefor | THE UNIVERSITY OF TOKYO (JP) | 2020-11-17 | — | — | US | disclosed |
| US-20190111418-A1 | COMPOUND AND SYNTHESIS METHOD THEREFOR | THE UNIVERSITY OF TOKYO (JP) | 2019-04-18 | — | — | US | disclosed |
| US-6194593-B1 | USEFUL AS LIGAND FOR AN ASYMMETRIC CATALYST FOR USE IN ASYMMETRICAL HYDROGENATION | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2001-02-27 | — | — | US | disclosed |
| JP-2000319288-A | OPTICALLY ACTIVE 1-2-BIS(DIALKYLPHOSPHINO)BENZENE DERIVATIVE AND ITS PRODUCTION, AND RHODIUM METAL COMPLEX WITH THE SAME AS LIGAND | NIPPON CHEM IND CO LTD | 2000-11-21 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10835895-B2 | Compound and synthesis method therefor | GOT1, GOT2, SLC39A11 | ALDH1A1 73/4885L3MBTL1 3751/4885ESR1 4158/4885 |
| US-20190111418-A1 | COMPOUND AND SYNTHESIS METHOD THEREFOR | GOT1, GOT2, SLC39A11 | ALDH1A1 90/4885L3MBTL1 3689/4885ESR1 4202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.