SCHEMBL7900995

SCHEMBL7900995

NC(=O)c1c(O)c(-c2ccccc2Cl)cc2ccccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 2/20 0.43
HSD17B10 Q99714 2/20 0.42
KMT2A Q03164 4/20 0.41
KDM4E B2RXH2 4/20 0.41
ALDH1A1 P00352 3/20 0.41
GLA P06280 2/20 0.41
MEN1 O00255 2/20 0.41
CYP1A2 P05177 1/20 0.41
HPGD P15428 1/20 0.41
CYP2C19 P33261 1/20 0.41
IKBKB O14920 2/20 0.40
MIF P14174 1/20 0.39
ATM Q13315 1/20 0.38
NQO1 P15559 1/20 0.38
SLC9A1 P19634 1/20 0.38
ABCG2 Q9UNQ0 1/20 0.37
GAA P10253 1/20 0.37
CYP11B1 P15538 1/20 0.37
CYP11B2 P19099 1/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5553181 0.80 MEN1 (0.49) GRM2HSD17B10KMT2AKDM4EALDH1A1
SCHEMBL2354413 0.78 KMT2A (0.50) HSD17B10KMT2AKDM4EALDH1A1GLA
SCHEMBL7949396 0.75 MCL1 (0.49) CYP1A2CYP2C19
SCHEMBL7946122 0.73 PAK1 (0.40) GRM2CYP1A2CYP2C19IKBKB
SCHEMBL5749296 0.73 ALDH1A1 (0.65) HSD17B10KMT2AKDM4EALDH1A1GLA
SCHEMBL9624322 0.72 POLB (0.59) HSD17B10KMT2AKDM4EALDH1A1GLA
Hydrochloric Acid SCHEMBL27651681 0.71 ALDH1A1 (0.63) HSD17B10KMT2AKDM4EALDH1A1GLA
SCHEMBL14241917 0.71 ALDH1A1 (0.50) HSD17B10KDM4EALDH1A1GLACYP1A2
SCHEMBL3454685 0.71 KDM4E (0.52) HSD17B10KMT2AKDM4EALDH1A1GLA
SCHEMBL10987170 0.71 TSPO (0.58) GRM2HSD17B10KMT2AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6184362-B1 Electrophotographic photoconductor, azo compounds for use in the same, and intermediates for producing the azo compounds RICOH COMPANY, LTD. (JP) 2001-02-06 US disclosed
US-6103435-A A COMPOUND HAVING AN AZO CHARGE GENERATING MOIETY AND A TRIARYLAMINO CHARGE TRANSPORTING MOIETY IN THE MOLECULE RICOH COMPANY, LTD. (JP) 2000-08-15 US disclosed
US-5459247-A Bisazo compounds useful as charge generating materials RICOH COMPANY, LTD. (JP) 1995-10-17 US disclosed
US-5317093-A Disazo, fluorene dyes for electrography RICOH COMPANY, LTD. (JP) 1994-05-31 US disclosed