Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGAV | P06756 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.31 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.31 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7898847 | 0.92 | MMP13 (0.35) | PABPC1ITGB3ITGB1ITGAVITGA2B | |
| SCHEMBL7900974 | 0.91 | PABPC1 (0.32) | PABPC1KLK5 | |
| SCHEMBL7897783 | 0.90 | PABPC1 (0.33) | PABPC1KLK5 | |
| SCHEMBL7900833 | 0.89 | PABPC1 (0.34) | PABPC1KLK5HRH2HRH1ATM | |
| SCHEMBL2791534 | 0.89 | MMP13 (0.34) | PABPC1KLK5 | |
| SCHEMBL2789039 | 0.88 | GFER (0.34) | GFERACKR3 | |
| SCHEMBL2789036 | 0.88 | GFER (0.34) | GFERACKR3 | |
| SCHEMBL7899253 | 0.88 | PABPC1 (0.32) | PABPC1KLK5ACKR3 | |
| SCHEMBL2790403 | 0.88 | PABPC1 (0.32) | PABPC1GFERKLK5ATM | |
| SCHEMBL2790406 | 0.88 | PABPC1 (0.32) | PABPC1GFERKLK5ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |