SCHEMBL7901523

SCHEMBL7901523

c1ccc(OC[C@H]2CCCN2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 10/20 0.79
CHRNB4 P30926 1/20 0.68
CHRNA3 P32297 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4155746 1.00 LTA4H (0.79) LTA4HCHRNB4CHRNA3
SCHEMBL5332805 1.00 LTA4H (0.79) LTA4HCHRNB4CHRNA3
Hydrochloric Acid SCHEMBL9237449 0.98 LTA4H (0.77) LTA4HCHRNB4CHRNA3
Hydrochloric Acid SCHEMBL4742124 0.98 LTA4H (0.77) LTA4HCHRNB4CHRNA3
SCHEMBL3166997 0.95 LTA4H (0.88) LTA4H
SCHEMBL4317030 0.94 LTA4H (0.91) LTA4H
SCHEMBL14544796 0.94 LTA4H (0.91) LTA4H
SCHEMBL4317023 0.94 LTA4H (0.91) LTA4H
SCHEMBL10326529 0.90 LTA4H (0.84) LTA4H
SCHEMBL10326840 0.90 LTA4H (0.84) LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240254136-A1 COMPOUNDS TARGETING RNA-BINDING PROTEINS OR RNA-MODIFYING PROTEINS Redona Therapeutics, Inc. 2024-08-01 US disclosed
CN-116157392-A Compounds targeting RNA binding proteins or RNA modification proteins 雷多纳治疗公司 2023-05-23 CN disclosed
EP-4114831-A1 COMPOUNDS TARGETING RNA-BINDING PROTEINS OR RNA-MODIFYING PROTEINS Twentyeight-Seven, Inc. (US) 2023-01-11 EP disclosed
CN-107667097-B Separation of enantiomers of 3-ethylbicyclo [3.2.0] hept-3-en-6-one 诺瓦色生物公司 2021-02-12 CN disclosed
EP-3303308-B1 SEPARATION OF ENANTIOMERS OF 3-ETHYLBICYCLO[3.2.0]HEPT-3-EN-6-ONE NOVASSAY SA (CH) 2019-10-09 EP disclosed
US-10150723-B2 Separation of enantiomers of 3-ethylbicyclo[3.2.0]hept-3-en-6-one NOVASSAY S.A. (CH) 2018-12-11 US disclosed
EP-2792664-B1 OPTICAL RESOLUTION METHOD FOR BICYCLIC COMPOUND USING ASYMMETRIC CATALYST DAIICHI SANKYO CO LTD (JP) 2018-07-04 EP disclosed
US-20180134643-A1 SEPARATION OF ENANTIOMERS OF 3-ETHYLBICYCLO[3.2.0]HEPT-3-EN-6-ONE NOVASSAY S.A. (CH) 2018-05-17 US disclosed
EP-3303308-A1 SEPARATION OF ENANTIOMERS OF 3-ETHYLBICYCLO[3.2.0]HEPT-3-EN-6-ONE Novassay SA (CH) 2018-04-11 EP disclosed
WO-2016146299-A1 SEPARATION OF ENANTIOMERS OF 3-ETHYLBICYCLO[3.2.0]HEPT-3-EN-6-ONE NOVASSAY SA (CH) 2016-09-22 WO disclosed
EP-2792664-A1 OPTICAL RESOLUTION METHOD FOR BICYCLIC COMPOUND USING ASYMMETRIC CATALYST DAIICHI SANKYO COMPANY, LIMITED (JP) 2014-10-22 EP disclosed
EP-2792664-A1 OPTICAL RESOLUTION METHOD FOR BICYCLIC COMPOUND USING ASYMMETRIC CATALYST DAIICHI SANKYO COMPANY, LIMITED (JP) 2014-10-22 EP disclosed
US-20140296569-A1 Optical Resolution Method for Bicyclic Compound Using Asymmetric Catalyst DAIICHI SANKYO COMPANY, LIMITED (JP) 2014-10-02 US disclosed
US-20140296569-A1 Optical Resolution Method for Bicyclic Compound Using Asymmetric Catalyst DAIICHI SANKYO COMPANY, LIMITED (JP) 2014-10-02 US disclosed
US-20140296569-A1 Optical Resolution Method for Bicyclic Compound Using Asymmetric Catalyst DAIICHI SANKYO COMPANY, LIMITED (JP) 2014-10-02 US disclosed
US-8546406-B2 Heterocyclic compounds as metap-2 inhibitors MERCK PATENT GMBH (DE) 2013-10-01 US disclosed
US-8546406-B2 Heterocyclic compounds as metap-2 inhibitors MERCK PATENT GMBH (DE) 2013-10-01 US disclosed
US-20110281859-A1 NOVEL HETEROCYCLIC COMPOUNDS AS METAP-2 INHIBITORS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-11-17 US disclosed
US-20110281859-A1 NOVEL HETEROCYCLIC COMPOUNDS AS METAP-2 INHIBITORS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-11-17 US disclosed
WO-2010083870-A1 NOVEL HETEROCYCLIC COMPOUNDS FOR USE AS METAP-2 INHIBITORS MERCK PATENT GMBH (DE) 2010-07-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140296569-A1 Optical Resolution Method for Bicyclic Compound Using Asymmetric Catalyst OXER1, OCIAD2, AOC2 LTA4H 1738/4885CHRNB4 2928/4885CHRNA3 2198/4885
US-20180134643-A1 SEPARATION OF ENANTIOMERS OF 3-ETHYLBICYCLO[3.2.0]HEPT-3-EN-6-ONE ALDH7A1, OPRK1, SCN3A LTA4H 1321/4885CHRNB4 520/4885CHRNA3 95/4885
US-20110281859-A1 NOVEL HETEROCYCLIC COMPOUNDS AS METAP-2 INHIBITORS METAP2, METAP1, XPNPEP2 LTA4H 1135/4885CHRNB4 4849/4885CHRNA3 4806/4885
US-10150723-B2 Separation of enantiomers of 3-ethylbicyclo[3.2.0]hept-3-en-6-one ALDH7A1, OPRK1, SCN3A LTA4H 1321/4885CHRNB4 520/4885CHRNA3 95/4885
US-20240254136-A1 COMPOUNDS TARGETING RNA-BINDING PROTEINS OR RNA-MODIFYING PROTEINS NSUN3, NSUN2, RBM3 LTA4H 4601/4885CHRNB4 4780/4885CHRNA3 4659/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.