Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 11/20 | 0.57 |
| ▸ | MMP2 | P08253 | 7/20 | 0.57 |
| ▸ | MMP1 | P03956 | 5/20 | 0.48 |
| ▸ | MMP3 | P08254 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LGMN | Q99538 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7901571 | 0.92 | MMP13 (0.59) | MMP13MMP2MMP1MMP3ALDH1A1 | |
| SCHEMBL7513672 | 0.91 | MMP13 (0.59) | MMP13MMP2MMP1MMP3ALDH1A1 | |
| SCHEMBL7508581 | 0.91 | MMP13 (0.53) | MMP13MMP2MMP1MMP3ALDH1A1 | |
| SCHEMBL7547380 | 0.87 | MMP2 (0.41) | MMP13MMP2MMP1MMP3ALDH1A1 | |
| SCHEMBL7509339 | 0.83 | MMP13 (0.61) | MMP13MMP2MMP1MMP3ALDH1A1 | |
| SCHEMBL7512022 | 0.81 | MMP2 (0.48) | MMP13MMP2MMP1MMP3ALDH1A1 | |
| SCHEMBL7509695 | 0.80 | MMP2 (0.58) | MMP13MMP2MMP1MMP3ALDH1A1 | |
| SCHEMBL7510414 | 0.80 | MMP2 (0.56) | MMP13MMP2MMP1MMP3ALDH1A1 | |
| SCHEMBL7511963 | 0.80 | MMP9 (0.58) | MMP13MMP2MMP1MMP3ALDH1A1 | |
| SCHEMBL7502278 | 0.78 | MMP13 (0.55) | MMP13MMP2MMP1MMP3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165501-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2002-01-02 | — | — | EP | disclosed |
| US-6197770-B1 | ENZYME INHIBITORS; ANTIARTHRITIC AGENTS; BONE DISORDERS | THE PROCTER & GAMBLE CO. | 2001-03-06 | — | — | US | disclosed |
| WO-2000051975-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-08 | — | — | WO | disclosed |