Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 13/20 | 0.59 |
| ▸ | MMP2 | P08253 | 12/20 | 0.59 |
| ▸ | MMP3 | P08254 | 7/20 | 0.59 |
| ▸ | MMP1 | P03956 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 2/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.42 |
| ▸ | BMP1 | P13497 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7509339 | 0.92 | MMP13 (0.61) | MMP13MMP2MMP3MMP1ALDH1A1 | |
| SCHEMBL7595438 | 0.91 | MMP13 (0.57) | MMP13MMP2MMP3MMP1ALDH1A1 | |
| SCHEMBL7509695 | 0.89 | MMP2 (0.58) | MMP13MMP2MMP3MMP1ALDH1A1 | |
| SCHEMBL7550995 | 0.87 | MMP13 (0.44) | MMP13MMP2MMP3MMP1ALDH1A1 | |
| SCHEMBL7516046 | 0.85 | MMP13 (0.48) | MMP13MMP2MMP3MMP1ALDH1A1 | |
| SCHEMBL7446582 | 0.85 | L3MBTL1 (0.47) | MMP13MMP2MMP3MMP1ALDH1A1 | |
| SCHEMBL7513743 | 0.84 | MMP13 (0.61) | MMP13MMP2MMP3MMP1ALDH1A1 | |
| SCHEMBL7901571 | 0.83 | MMP13 (0.59) | MMP13MMP2MMP3MMP1ALDH1A1 | |
| SCHEMBL7508581 | 0.82 | MMP13 (0.53) | MMP13MMP2MMP3MMP1ALDH1A1 | |
| SCHEMBL7506693 | 0.82 | MMP2 (0.51) | MMP13MMP2MMP3MMP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165501-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2002-01-02 | — | — | EP | disclosed |
| US-6197770-B1 | ENZYME INHIBITORS; ANTIARTHRITIC AGENTS; BONE DISORDERS | THE PROCTER & GAMBLE CO. | 2001-03-06 | — | — | US | disclosed |
| WO-2000051975-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-08 | — | — | WO | disclosed |