Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29082976 | 0.91 | ALDH1A1 (0.44) | TDP1TP53ACHECYP3A4HTT | |
| SCHEMBL11694484 | 0.87 | TP53 (0.37) | TDP1TP53CYP3A4HTTCYP1A2 | |
| SCHEMBL10694157 | 0.86 | CHKA (0.41) | TDP1CYP3A4MAPTPTPN1UTS2R | |
| SCHEMBL9292809 | 0.81 | RECQL (0.41) | TDP1TP53ACHECYP3A4HTT | |
| SCHEMBL15324519 | 0.79 | CRHR1 (0.41) | ALDH1A1SIGMAR1CHKALMNAC5AR1 | |
| SCHEMBL2516873 | 0.79 | SLC6A2 (0.49) | HTTCYP2C9CYP2C19CYP2D6RECQL | |
| SCHEMBL10931233 | 0.78 | NFE2L2 (0.39) | ACHECYP3A4CYP1A2CYP2D6PTPN1 | |
| SCHEMBL564593 | 0.78 | CYP2A6 (0.46) | TDP1CYP1A2ALDH1A1SIGMAR1CHKA | |
| SCHEMBL5306209 | 0.77 | ALDH1A1 (0.58) | ACHECYP3A4MAPTPTPN1ALDH1A1 | |
| SCHEMBL609647 | 0.77 | TDP1 (0.44) | TDP1TP53CYP3A4MAPTPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4607124-A | REACTING SQUARIC ACID, AROMATIC AMINE AND A FLUOROANILINE IN PRESENCE OF ALIPHATIC ALCOHOL | XEROX CORPORATION (US) | 1986-08-19 | — | — | US | claimed |
| US-9588123-B2 | Compositions and methods for in vitro diagnostic tests including zwitterionic solubilization reagent | SURMODICS IVD, INC. (US) | 2017-03-07 | — | — | US | disclosed |
| EP-2841592-B1 | COMPOSITIONS AND METHODS FOR IN VITRO DIAGNOSTIC TESTS INCLUDING SULFONIC ACID | SURMODICS INC (US) | 2017-02-22 | — | — | EP | disclosed |
| US-9229005-B2 | Compositions and methods for in vitro diagnostic tests including sulfonic acid compound | SURMODICS IVD, INC. (US) | 2016-01-05 | — | — | US | disclosed |
| US-20150293110-A1 | COMPOSITIONS AND METHODS FOR IN VITRO DIAGNOSTIC TESTS INCLUDING ZWITTERIONIC SOLUBILIZATION REAGENT | BANK OF MONTREAL, AS COLLATERAL AGENT | 2015-10-15 | — | — | US | disclosed |
| WO-2015157637-A1 | COMPOSITIONS AND METHODS FOR IN VITRO DIAGNOSTIC TESTS INCLUDING ZWITTERIONIC SOLUBILIZATION REAGENT | SURMODICS IVD, INC. (US) | 2015-10-15 | — | — | WO | disclosed |
| US-8927226-B2 | Compositions and methods for in vitro diagnostic tests including sulfonic acid | SURMODICS, INC. (US) | 2015-01-06 | — | — | US | disclosed |
| US-20140234874-A1 | COMPOSITIONS AND METHODS FOR IN VITRO DIAGNOSTIC TESTS INCLUDING SULFONIC ACID | SURMODICS, INC. (US) | 2014-08-21 | — | — | US | disclosed |
| US-20130252261-A1 | COMPOSITIONS AND METHODS FOR IN VITRO DIAGNOSTIC TESTS INCLUDING SULFONIC ACID COMPOUND | BANK OF MONTREAL, AS COLLATERAL AGENT | 2013-09-26 | — | — | US | disclosed |
| EP-1082453-A1 | LIQUID REAGENT SET FOR L-LACTATE DETERMINATION | Roche Diagnostics Corporation (US) | 2001-03-14 | — | — | EP | disclosed |
| US-6030802-A | Liquid reagent set for L-lactate determination | ROCHE DIAGNOSTICS CORPORATION (US) | 2000-02-29 | — | — | US | disclosed |
| WO-1999061657-A1 | LIQUID REAGENT SET FOR L-LACTATE DETERMINATION | ROCHE DIAGNOSTICS CORPORATION (US) | 1999-12-02 | — | — | WO | disclosed |
| EP-0415471-B1 | Stabilized Trinder reagent | INSTRUMENTATION LAB SPA (IT) | 1994-11-09 | — | — | EP | disclosed |
| US-5206006-A | Peroxidase enzyme; phenylpyrazone derivative phenol or aromatic amine; stabilizer; storage discoloration inhibition | INSTRUMENTATION LABORATORY SPA (IT) | 1993-04-27 | — | — | US | disclosed |
| US-5108733-A | Inhibiting coloration development by adding stabilizers | INSTRUMENTATION LABORATORY S.P.A. (IT) | 1992-04-28 | — | — | US | disclosed |
| EP-0415471-A2 | Stabilized Trinder reagent | INSTRUMENTATION LABORATORY S.p.A. (IT) | 1991-03-06 | — | — | EP | disclosed |
| EP-0012350-B1 | AZO DYESTUFFS, THEIR PREPARATION AND THEIR USE IN THE DYEING OF N-CONTAINING MATERIALS | BAYER AG (DE) | 1982-04-07 | — | — | EP | disclosed |
| EP-0012350-A1 | Azo dyestuffs, their preparation and their use in the dyeing of N-containing materials | BAYER AG (DE) | 1980-06-25 | — | — | EP | disclosed |