Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.38 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.37 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694157 | 0.86 | CHKA (0.41) | PTPN1UTS2RCHKAALDH1A1OPRM1 | |
| SCHEMBL7223872 | 0.81 | PYCR1 (0.42) | MTNR1AMTNR1BPYCR1ALDH1A1MAPK1 | |
| SCHEMBL10931233 | 0.78 | NFE2L2 (0.39) | PTPN1UTS2RCHKAMAPK1TAAR1 | |
| SCHEMBL609647 | 0.77 | TDP1 (0.44) | PTPN1UTS2RCHKAALDH1A1OPRM1 | |
| SCHEMBL28449319 | 0.77 | MAPT (0.56) | PTPN1UTS2RCHKATAAR1S1PR1 | |
| SCHEMBL5306209 | 0.77 | ALDH1A1 (0.58) | PTPN1CHKAALDH1A1OPRM1OPRK1 | |
| SCHEMBL8118911 | 0.77 | PTPN1 (0.38) | PTPN1UTS2RCHKAALDH1A1OPRM1 | |
| SCHEMBL10978579 | 0.77 | CYP3A4 (0.41) | PTPN1UTS2RCHKAALDH1A1MAPK1 | |
| SCHEMBL7902533 | 0.77 | TDP1 (0.44) | PTPN1UTS2RCHKAALDH1A1MAPK1 | |
| SCHEMBL5824161 | 0.76 | S1PR1 (0.39) | PTPN1UTS2RCHKAALDH1A1S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110872314-A | Asymmetric silicon-based substituted rhodamine derivative, and preparation method and application thereof | 华东师范大学 | 2020-03-10 | — | — | CN | claimed |
| US-20260085080-A1 | CYCLIC GERMANIUM COMPOUNDS AND APPLICATIONS THEREOF | UNIV MISSOURI (US) | 2026-03-26 | — | — | US | disclosed |
| US-12441749-B2 | Cyclic germanium compounds and applications thereof | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2025-10-14 | — | — | US | disclosed |
| US-20250115628-A1 | FLUORINATED FLUOROPHORES | HOWARD HUGHES MEDICAL INSTITUTE | 2025-04-10 | — | — | US | disclosed |
| US-20240239823-A1 | PHOSPHINATE ESTER-CONTAINING DYES HAVING TUNABLE PROPERTIES AND METHODS OF MAKING THE SAME | NUTECH VENTURES | 2024-07-18 | — | — | US | disclosed |
| EP-2970342-B1 | SUBSTITUTED SILAXANTHENIUM RED TO NEAR-INFRARED FLUOROCHROMES FOR IN VITRO AND IN VIVO IMAGING AND DETECTION | VISEN MEDICAL INC (US) | 2024-01-24 | — | — | EP | disclosed |
| EP-2970342-B1 | SUBSTITUTED SILAXANTHENIUM RED TO NEAR-INFRARED FLUOROCHROMES FOR IN VITRO AND IN VIVO IMAGING AND DETECTION | VISEN MEDICAL INC (US) | 2024-01-24 | — | — | EP | disclosed |
| WO-2023219136-A1 | FLUORESCENT PROBE FOR DETECTING PEPTIDE-LINKED HYDROLASE | 国立大学法人 東京大学 | 2023-11-16 | — | — | WO | disclosed |
| CN-114849787-B | Aryl bidentate phosphine ligand polymer in-situ encapsulation rhodium-based catalytic material and preparation method and application thereof | 中国科学院兰州化学物理研究所 | 2023-07-28 | — | — | CN | disclosed |
| US-11591359-B2 | Enzyme-specific intracellularly-retained red fluorescent probe | THE UNIVERSITY OF TOKYO (JP) | 2023-02-28 | — | — | US | disclosed |
| US-20140057312-A1 | FLUORESCENT PROBE | THE UNIVERSITY OF TOKYO (JP) | 2014-02-27 | — | — | US | disclosed |
| US-20140057312-A1 | FLUORESCENT PROBE | THE UNIVERSITY OF TOKYO (JP) | 2014-02-27 | — | — | US | disclosed |
| US-20140051863-A1 | FLUORESCENT PROBES FOR DETECTION OF COPPER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2014-02-20 | — | — | US | disclosed |
| US-20140051863-A1 | FLUORESCENT PROBES FOR DETECTION OF COPPER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2014-02-20 | — | — | US | disclosed |
| US-20140051863-A1 | FLUORESCENT PROBES FOR DETECTION OF COPPER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2014-02-20 | — | — | US | disclosed |
| WO-2013188421-A1 | CYCLIC GERMANIUM COMPOUNDS AND APPLICATIONS THEREOF | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2013-12-19 | — | — | WO | disclosed |
| US-20130289256-A1 | FLUORESCENT PROBE | THE UNIVERSITY OF TOKYO (JP) | 2013-10-31 | — | — | US | disclosed |
| US-20130289256-A1 | FLUORESCENT PROBE | THE UNIVERSITY OF TOKYO (JP) | 2013-10-31 | — | — | US | disclosed |
| US-20130289256-A1 | FLUORESCENT PROBE | THE UNIVERSITY OF TOKYO (JP) | 2013-10-31 | — | — | US | disclosed |
| US-6121296-A | ADMINISTERING TO TREAT PARASITIC INFECTION OR DISEASE OR TO TREAT INFECTIONS AND DISEASES CAUSED BY CERTAIN BACTERIAL AND PLANT TOXINS; COMPOUNDS SUCH AS SALT OF 2-PHENYL-3,4-DIHYDROXY-5-HYDROXYMETHYL-PYRROLIDINE | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2000-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239823-A1 | PHOSPHINATE ESTER-CONTAINING DYES HAVING TUNABLE PROPERTIES AND METHODS OF MAKING THE SAME | PPOX, PNPO, PHOSPHO1 | PTPN1 638/4885MTNR1A 3622/4885MTNR1B 4147/4885 |
| US-20260085080-A1 | CYCLIC GERMANIUM COMPOUNDS AND APPLICATIONS THEREOF | CRY2, NR2E3, TRPC6 | PTPN1 3550/4885MTNR1A 2575/4885MTNR1B 3317/4885 |
| US-20140051863-A1 | FLUORESCENT PROBES FOR DETECTION OF COPPER | NCS1, CHERP, RYR1 | PTPN1 4503/4885MTNR1A 1419/4885MTNR1B 1890/4885 |
| US-11591359-B2 | Enzyme-specific intracellularly-retained red fluorescent probe | GLB1, GUSB, GLA | PTPN1 4366/4885MTNR1A 1158/4885MTNR1B 1920/4885 |
| US-20250115628-A1 | FLUORINATED FLUOROPHORES | PFAS, FLI1, ARFGEF1 | PTPN1 4774/4885MTNR1A 4128/4885MTNR1B 3667/4885 |
| US-12441749-B2 | Cyclic germanium compounds and applications thereof | GMNN, DCX, TRPA1 | PTPN1 3910/4885MTNR1A 4633/4885MTNR1B 4745/4885 |
| US-20130289256-A1 | FLUORESCENT PROBE | HNRNPH3, H1-3, REL | PTPN1 4044/4885MTNR1A 1733/4885MTNR1B 1805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.