Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9069667 | 0.82 | POLB (0.36) | HTR2APOLBGPR3 | |
| Hydrochloric Acid SCHEMBL9246573 | 0.74 | POLB (0.36) | HTR2APOLBGPR3 | |
| Hydrochloric Acid SCHEMBL3783189 | 0.72 | HTR2A (0.35) | HTR2APOLBGPR3 | |
| Hydrochloric Acid SCHEMBL2355388 | 0.70 | POLB (0.30) | POLB | |
| Bromide SCHEMBL7205884 | 0.69 | HTR2A (0.35) | HTR2APOLBGPR3 | |
| Hydrochloric Acid SCHEMBL6553648 | 0.64 | GPR3 (0.35) | HTR2APOLBGPR3 | |
| Hydrochloric Acid SCHEMBL6897416 | 0.63 | POLB (0.32) | POLB | |
| SCHEMBL7030170 | 0.62 | POLB (0.34) | HTR2APOLBGPR3 | |
| Hydrochloric Acid SCHEMBL7095854 | 0.62 | POLB (0.34) | HTR2APOLBGPR3 | |
| Hydrochloric Acid SCHEMBL7941237 | 0.62 | EPHX2 (0.32) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197902-B1 | Syndio-isoblock polymer and process for its preparation | TARGOR GMBH (DE) | 2001-03-06 | — | — | US | disclosed |