Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7719938 | 0.72 | POLB (0.33) | POLBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9246573 | 0.64 | POLB (0.36) | POLBKMT2A | |
| Hydrochloric Acid SCHEMBL7902589 | 0.63 | HTR2A (0.33) | POLB | |
| Hydrochloric Acid SCHEMBL3783189 | 0.62 | HTR2A (0.35) | POLB | |
| SCHEMBL9285789 | 0.60 | DRD2 (0.40) | POLBMEN1KMT2A | |
| Bromide SCHEMBL7205884 | 0.58 | HTR2A (0.35) | POLB | |
| SCHEMBL29116619 | 0.58 | HTR2A (0.50) | MEN1KMT2A | |
| SCHEMBL25171318 | 0.57 | LMNA (0.54) | — | |
| SCHEMBL70993 | 0.57 | LMNA (0.54) | — | |
| SCHEMBL29370508 | 0.57 | LMNA (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874859-B1 | OPEN-PENTADIENYL METALLOCENES, PRECURSORS THEREOF AND POLYMERIZATION CATALYSTS THEREFROM | BASELL POLYOLEFINE GMBH (DE) | 2004-03-17 | — | — | EP | disclosed |