Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.48 |
| ▸ | ATR | Q13535 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 2/20 | 0.41 |
| ▸ | FPR1 | P21462 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 3/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 2/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL790786 | 0.85 | ALDH1A1 (0.52) | PI4KAPIK3CGJAK2FPR1FPR2 | |
| SCHEMBL790553 | 0.85 | ATR (0.49) | PI4KAPIK3CGATRJAK2BRAF | |
| SCHEMBL789511 | 0.76 | SMN1; SMN2 (0.59) | ATRMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL790788 | 0.76 | NPC1 (0.54) | ATRJAK2DGAT1 | |
| SCHEMBL807273 | 0.75 | ALDH1A1 (0.53) | PI4KAPIK3CGJAK2ALDH1A1 | |
| SCHEMBL3784845 | 0.75 | MAPT (0.51) | JAK2FPR1FPR2BRAFDGAT1 | |
| SCHEMBL789721 | 0.73 | MAPK14 (0.51) | BRAFRAF1MEN1ALDH1A1MAPT | |
| Formic Acid SCHEMBL790534 | 0.72 | ALDH1A1 (0.50) | PI4KAPIK3CGJAK2ALDH1A1DYRK1A | |
| SCHEMBL789670 | 0.72 | PI4KA (0.51) | PI4KAPIK3CGLRRK2FYNMEN1 | |
| SCHEMBL789696 | 0.72 | JAK2 (0.48) | PI4KAPIK3CGJAK2LRRK2FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |