Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | PI4KA | P42356 | 1/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.44 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.44 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.44 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 2/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL807273 | 0.90 | ALDH1A1 (0.53) | ALDH1A1PI4KAPIK3CGGBA1GLA | |
| Formic Acid SCHEMBL790534 | 0.87 | ALDH1A1 (0.50) | ALDH1A1PI4KAPIK3CGGBA1GLA | |
| SCHEMBL790400 | 0.85 | PI4KA (0.48) | ALDH1A1PI4KAPIK3CGMAPTDYRK1A | |
| SCHEMBL790553 | 0.85 | ATR (0.49) | PI4KAPIK3CGGSK3BMAPTJAK2 | |
| SCHEMBL790621 | 0.81 | KDR (0.46) | ALDH1A1GBA1GLAMAPTHPGD | |
| SCHEMBL789511 | 0.75 | SMN1; SMN2 (0.59) | ALDH1A1MAPTPIK3CAKMT2A | |
| SCHEMBL790788 | 0.75 | NPC1 (0.54) | JAK2JAK3JAK1 | |
| SCHEMBL789721 | 0.73 | MAPK14 (0.51) | ALDH1A1MAPTKMT2A | |
| SCHEMBL790535 | 0.72 | PI4KA (0.41) | PI4KAPIK3CGJAK2JAK3MAP4K4 | |
| SCHEMBL789670 | 0.71 | PI4KA (0.51) | ALDH1A1PI4KAPIK3CGMAPTPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |