Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | ALKBH1 | Q13686 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26087702 | 0.83 | MCL1 (0.66) | MCL1LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL31053884 | 0.83 | MCL1 (0.66) | MCL1LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL6534698 | 0.81 | CYP1A2 (0.62) | ALKBH1LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL7838019 | 0.81 | ESR2 (0.50) | MCL1ALKBH1LMNACYP1A2PTGS1 | |
| SCHEMBL28658874 | 0.80 | ALKBH1 (0.50) | MCL1ALKBH1LMNAP4HTMMEN1 | |
| SCHEMBL7793991 | 0.80 | XDH (0.53) | XDH | |
| SCHEMBL7779413 | 0.79 | LMNA (0.59) | MCL1LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL28646599 | 0.77 | RAB9A (0.52) | ALKBH1LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL8993237 | 0.77 | ERN1 (0.58) | MCL1LMNAKDM4EMGLL | |
| SCHEMBL8572314 | 0.77 | NPC1 (0.57) | MCL1ALKBH1LMNACYP1A2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100338175-C | Chiral liquid crystal compounds having fluorine-containing terminal moieties | MINNESOTA MINING & MFG (US) | 2007-09-19 | — | — | CN | disclosed |
| CN-1326494-A | Chiral liquid crystal compounds having fluorinated terminal portion | MINNESOTA MINING & MFG (US) | 2001-12-12 | — | — | CN | disclosed |
| EP-1135450-A1 | CHIRAL LIQUID CRYSTAL COMPOUNDS HAVING A FLUORINATED TERMINAL PORTION | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2001-09-26 | — | — | EP | disclosed |
| US-6139924-A | CONTAINING A PYRIMIDINE RING | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-10-31 | — | — | US | disclosed |
| WO-2000031210-A1 | CHIRAL LIQUID CRYSTAL COMPOUNDS HAVING A FLUORINATED TERMINAL PORTION | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-06-02 | — | — | WO | disclosed |
| US-5928562-A | HAVING EXTENDED HYDROCARBON ETHER GROUP ADJACENT TO A TERMINAL FLUOROALKYL OR FLUOROETHER GROUP; LOW VISCOSITY; HIGH SPEED RESPONSE; BRIGHTNESS; COMMPATIBILITY; DISPLAYS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-07-27 | — | — | US | disclosed |