Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7903787 | 0.91 | HTR7 (0.37) | ALDH1A1KDM4EATMHTR1B | |
| SCHEMBL7903918 | 0.89 | ATM (0.34) | ALDH1A1KDM4EATMHTR1B | |
| SCHEMBL7902642 | 0.81 | HTR1B (0.36) | ALDH1A1KDM4EATMHTR1B | |
| SCHEMBL7904665 | 0.78 | HRH3 (0.36) | ALDH1A1KDM4EHPGDATMKMT2A | |
| SCHEMBL7904668 | 0.77 | ALDH1A1 (0.37) | ALDH1A1KDM4EDRD2DRD3PTPN1 | |
| SCHEMBL7896515 | 0.77 | HTR1B (0.38) | ALDH1A1KDM4EATMHTR1B | |
| SCHEMBL7905809 | 0.77 | KDM4E (0.36) | ALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL7904733 | 0.74 | RAB9A (0.40) | ALDH1A1KDM4EDRD2DRD3L3MBTL1 | |
| SCHEMBL7903818 | 0.73 | ATM (0.34) | ALDH1A1KDM4EATMHTR1B | |
| SCHEMBL7904672 | 0.72 | HTR1B (0.39) | ALDH1A1KDM4EATMHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191152-B1 | CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | EGIS GYÓGYSZERGYAR RT. (HU) | 2001-02-20 | — | — | US | disclosed |