Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7896515 | 0.90 | HTR1B (0.38) | KDM4EALDH1A1HRH3 | |
| SCHEMBL7902622 | 0.84 | KDM4E (0.36) | KDM4EALDH1A1HRH3HSD17B10HPGD | |
| SCHEMBL7902642 | 0.82 | HTR1B (0.36) | KDM4EALDH1A1HRH3HSD17B10 | |
| SCHEMBL7903985 | 0.81 | KDM4E (0.34) | KDM4EALDH1A1HRH3HSD17B10HPGD | |
| SCHEMBL7905780 | 0.80 | HRH3 (0.40) | KDM4EALDH1A1HRH3HSD17B10PTPN11 | |
| SCHEMBL7904672 | 0.80 | HTR1B (0.39) | KDM4EALDH1A1HRH3 | |
| SCHEMBL7904676 | 0.79 | RAB9A (0.33) | KDM4EALDH1A1HSD17B10HPGDMEN1 | |
| SCHEMBL7902606 | 0.79 | KDM4E (0.36) | KDM4EALDH1A1HRH3HSD17B10PTPN11 | |
| SCHEMBL7903918 | 0.79 | ATM (0.34) | KDM4EALDH1A1HRH3 | |
| SCHEMBL7904717 | 0.79 | MAOB (0.33) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191152-B1 | CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | EGIS GYÓGYSZERGYAR RT. (HU) | 2001-02-20 | — | — | US | disclosed |