Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.41 |
| ▸ | JAK2 | O60674 | 2/20 | 0.40 |
| ▸ | JAK1 | P23458 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.38 |
| ▸ | CCNK | O75909 | 1/20 | 0.38 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7898292 | 0.79 | BTK (0.42) | HPGDSGPR119JAK2JAK1ALDH1A1 | |
| SCHEMBL7901892 | 0.77 | MAPK1 (0.49) | HPGDSGPR119JAK2JAK1ALDH1A1 | |
| SCHEMBL7898726 | 0.76 | USP30 (0.46) | GPR119ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL7901250 | 0.76 | HTR6 (0.45) | HPGDSGPR119JAK2JAK1ALDH1A1 | |
| SCHEMBL7906014 | 0.76 | GPR119 (0.39) | HPGDSGPR119JAK2JAK1ALDH1A1 | |
| SCHEMBL7905938 | 0.73 | ALOX5AP (0.37) | HPGDSGPR119ALDH1A1MEN1MAPT | |
| SCHEMBL25343613 | 0.70 | PDE4B (0.52) | HPGDSGPR119JAK2JAK1ALDH1A1 | |
| SCHEMBL26667052 | 0.70 | PDE4B (0.52) | HPGDSGPR119JAK2JAK1ALDH1A1 | |
| SCHEMBL7900422 | 0.69 | BTK (0.44) | HPGDSGPR119JAK2JAK1ALDH1A1 | |
| SCHEMBL22605772 | 0.69 | GPR119 (0.49) | GPR119JAK2JAK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |