Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 5/20 | 0.46 |
| ▸ | FABP4 | P15090 | 4/20 | 0.44 |
| ▸ | FABP3 | P05413 | 3/20 | 0.44 |
| ▸ | PRNP | P04156 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | PTGFR | P43088 | 6/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8792384 | 0.80 | DHODH (0.72) | LMNADHODHPTGFR | |
| SCHEMBL789402 | 0.78 | CYP1A2 (0.41) | DHODHPTGFR | |
| SCHEMBL790933 | 0.75 | APP (0.47) | LMNA | |
| SCHEMBL790759 | 0.75 | KDM4E (0.47) | LMNARXFP1 | |
| SCHEMBL789718 | 0.75 | CYP1A1 (0.41) | DHODH | |
| SCHEMBL17594299 | 0.75 | DHODH (0.71) | DHODHPTGFR | |
| SCHEMBL17593597 | 0.75 | PTGFR (0.64) | LMNADHODHPTGFR | |
| SCHEMBL790753 | 0.73 | CYP1A2 (0.37) | PTGFR | |
| SCHEMBL10277681 | 0.73 | LRRK2 (0.47) | RXFP1 | |
| SCHEMBL10436444 | 0.72 | DHODH (0.61) | DHODHPTGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |