Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 10/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL790839 | 0.81 | ADORA2A (0.49) | KDM4EHSD17B10ALDH1A1HPGDADORA2A | |
| SCHEMBL789402 | 0.78 | CYP1A2 (0.41) | KDM4EALDH1A1HPGDADORA2AHTT | |
| SCHEMBL789847 | 0.76 | JAK2 (0.46) | KDM4EALDH1A1HPGDADORA2APIK3CD | |
| SCHEMBL1414662 | 0.75 | ADORA1 (0.39) | KDM4EHSD17B10ALDH1A1HPGDADORA2A | |
| SCHEMBL790933 | 0.75 | APP (0.47) | KDM4EHSD17B10ALDH1A1HPGDADORA2A | |
| SCHEMBL789718 | 0.75 | CYP1A1 (0.41) | KDM4EALDH1A1 | |
| SCHEMBL790609 | 0.75 | LMNA (0.48) | RXFP1LMNA | |
| SCHEMBL3319793 | 0.73 | ADORA2A (0.56) | KDM4EHSD17B10ALDH1A1HPGDADORA2A | |
| SCHEMBL4436700 | 0.73 | ADORA2A (0.60) | KDM4EHSD17B10ALDH1A1HPGDADORA2A | |
| SCHEMBL790753 | 0.73 | CYP1A2 (0.37) | KDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |