Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 3/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.33 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.33 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.33 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.33 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7908906 | 0.92 | PLAU (0.34) | MAPTRAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7916835 | 0.89 | PDE2A (0.35) | MAPTRAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL16502496 | 0.86 | MAPT (0.40) | MAPTRAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL16502499 | 0.85 | LMNA (0.48) | MAPTRAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7915719 | 0.83 | RAB9A (0.40) | MAPTRAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7920004 | 0.83 | PLAU (0.34) | MAPTRAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7916775 | 0.80 | PLAU (0.32) | PLAUPKM | |
| SCHEMBL7923024 | 0.79 | HTR5A (0.53) | HTR5A | |
| SCHEMBL16503543 | 0.79 | MAPT (0.43) | MAPTRAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7918428 | 0.78 | SLC6A4 (0.40) | MAPTRAB9ASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010090304-A1 | ACYLGUANIDINE DERIVATIVE | アステラス製薬株式会社 (JP) | 2010-08-12 | — | — | WO | disclosed |