Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 2/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | BAX | Q07812 | 2/20 | 0.42 |
| ▸ | PTPRC | P08575 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | S100A4 | P26447 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27413429 | 0.84 | HTR7 (0.46) | ALDH1A1MAPTLMNAHTR7SCN2A | |
| SCHEMBL14988299 | 0.84 | NPC1 (0.45) | ALDH1A1MAPTLMNAXDHKMT2A | |
| SCHEMBL30497064 | 0.82 | LMNA (0.60) | ALDH1A1LMNAXDHERN1KMT2A | |
| SCHEMBL11768743 | 0.82 | LMNA (0.60) | ALDH1A1LMNAXDHERN1KMT2A | |
| SCHEMBL28339189 | 0.81 | HTR7 (0.43) | ALDH1A1LMNAHTR7SCN2APOLB | |
| SCHEMBL18605359 | 0.81 | MAPT (0.52) | ALDH1A1MAPTLMNAERN1SCN2A | |
| SCHEMBL28240316 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MAPTLMNAHTR7SCN2A | |
| SCHEMBL4262386 | 0.79 | PTGS2 (0.52) | ALDH1A1MAPTERN1POLBKMT2A | |
| SCHEMBL7930381 | 0.79 | ERN1 (0.56) | ALDH1A1MAPTERN1POLBKMT2A | |
| SCHEMBL9664960 | 0.78 | TDP1 (0.60) | ALDH1A1MAPTLMNAXDHERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111094557-B | Alcohol dehydrogenase mutant and application thereof in synthesis of diaryl chiral alcohol | 江南大学 | 2022-11-11 | — | — | CN | disclosed |
| CN-111094557-A | Alcohol dehydrogenase mutant and application thereof in synthesis of diaryl chiral alcohol | 江南大学 | 2020-05-01 | — | — | CN | disclosed |
| US-9326930-B2 | Calcium sequestration compositions and methods of treating skin pigmentation disorders and conditions | NEOCUTIS S.A. (CH) | 2016-05-03 | — | — | US | disclosed |
| US-6217845-B1 | IMAGING; THERAPY | ANORMED, INC. (CA) | 2001-04-17 | — | — | US | disclosed |
| US-5753520-A | BIOCHEMICAL CONJUGATED WITH A HYDRAZINE OR A HYDRAZONE COMPOUND AS DRUG DELIVERY; HIGH BIOLOGICAL SPECIFICITY; MEDICINE FOR IMAGING, THERAPY, RADIOACTIVE TAGGING | JOHNSON MATTHEY INC. (US) | 1998-05-19 | — | — | US | disclosed |
| EP-0384769-B1 | Protein labelling | JOHNSON MATTHEY PLC (GB) | 1996-04-24 | — | — | EP | disclosed |
| US-5420285-A | Imaging for medicine | JOHNSON MATTHEY, INC. (US) | 1995-05-30 | — | — | US | disclosed |
| US-5206370-A | Certain pyridyl hydrazines and hydrazides useful for protein labeling | JOHNSON MATTHEY, INC. (US) | 1993-04-27 | — | — | US | disclosed |
| EP-0384769-A2 | Protein labelling | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 1990-08-29 | — | — | EP | disclosed |
| US-3966678-A | Maleic anhydride-polyaldimine prepolymers | RHONE-POULENC S.A. (FR) | 1976-06-29 | — | — | US | disclosed |