Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.39 |
| ▸ | JAK2 | O60674 | 5/20 | 0.38 |
| ▸ | JAK3 | P52333 | 5/20 | 0.38 |
| ▸ | JAK1 | P23458 | 4/20 | 0.38 |
| ▸ | TYK2 | P29597 | 3/20 | 0.38 |
| ▸ | ATR | Q13535 | 2/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL790534 | 0.82 | ALDH1A1 (0.50) | PI4KAPIK3CGMAP4K4JAK2JAK3 | |
| SCHEMBL807273 | 0.81 | ALDH1A1 (0.53) | PI4KAPIK3CGMAP4K4JAK2JAK3 | |
| SCHEMBL790788 | 0.80 | NPC1 (0.54) | MAPK14JAK2JAK3JAK1TYK2 | |
| SCHEMBL789721 | 0.78 | MAPK14 (0.51) | MAPK14BRAFBTK | |
| SCHEMBL789511 | 0.77 | SMN1; SMN2 (0.59) | MAPK14ATR | |
| SCHEMBL789670 | 0.76 | PI4KA (0.51) | PI4KAPIK3CGFYN | |
| SCHEMBL789696 | 0.74 | JAK2 (0.48) | PI4KAPIK3CGJAK2FYN | |
| SCHEMBL790553 | 0.72 | ATR (0.49) | PI4KAPIK3CGMAPK14JAK2JAK3 | |
| SCHEMBL790786 | 0.72 | ALDH1A1 (0.52) | PI4KAPIK3CGMAP4K4JAK2JAK3 | |
| SCHEMBL790400 | 0.71 | PI4KA (0.48) | PI4KAPIK3CGJAK2ATRBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |