Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33832 | 0.77 | TDP1 (0.46) | ALDH1A1TSHRMEN1KMT2ATDP1 | |
| SCHEMBL7136437 | 0.77 | TDP1 (0.46) | ALDH1A1TSHRMEN1KMT2ATDP1 | |
| SCHEMBL6129444 | 0.75 | SMN1; SMN2 (0.38) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL2075135 | 0.75 | MAPT (0.36) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL1179476 | 0.75 | HPGD (0.38) | LMNAALDH1A1TSHRKMT2ATDP1 | |
| SCHEMBL2193445 | 0.75 | LMNA (0.33) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL1179579 | 0.75 | PDE7A (0.35) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL455622 | 0.75 | ALDH1A1 (0.48) | LMNAALDH1A1TSHRTDP1 | |
| SCHEMBL3042315 | 0.75 | GPR35 (0.42) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL3556690 | 0.75 | ALDH1A1 (0.34) | LMNAALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211234-B1 | BENZONITRILE COMPOUNDS WITH ETHER AND SULFIDE GROUPS WITH CARBOXY ACID | RHONE-POULENC RORER LIMITED (GB) | 2001-04-03 | — | — | US | disclosed |
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | disclosed |
| EP-0728128-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995013262-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1995-05-18 | — | — | WO | disclosed |