Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LSS | P48449 | 3/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.34 |
| ▸ | AGER | Q15109 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7903918 | 0.85 | ATM (0.34) | KDM4EHRH3ALDH1A1 | |
| SCHEMBL7896435 | 0.85 | NR1H4 (0.34) | RAB9ALMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL7905953 | 0.81 | RAB9A (0.45) | RAB9ALMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL7903787 | 0.80 | HTR7 (0.37) | KDM4ESMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7908541 | 0.80 | RAB9A (0.44) | RAB9ALMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL7908470 | 0.77 | HRH3 (0.44) | RAB9ALMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL7903921 | 0.76 | SMN1; SMN2 (0.37) | KDM4ESMN1; SMN2 | |
| SCHEMBL7896538 | 0.76 | RAB9A (0.43) | RAB9ALMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL7908482 | 0.74 | ALDH1A1 (0.32) | LMNAKDM4EL3MBTL1DRD2DRD3 | |
| SCHEMBL7902642 | 0.73 | HTR1B (0.36) | KDM4EHRH3HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191152-B1 | CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | EGIS GYÓGYSZERGYAR RT. (HU) | 2001-02-20 | — | — | US | disclosed |