Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7908500 | 0.89 | PIK3CA (0.41) | MAPTPIK3CASMN1; SMN2MTORPKM | |
| Tetrabuthylammonium SCHEMBL7896503 | 0.81 | TLR8 (0.39) | TLR8MAPTTRPM8MAPK1 | |
| Tetrabuthylammonium SCHEMBL8458162 | 0.79 | TLR8 (0.37) | TLR8MAPTSMN1; SMN2HTTTRPM8 | |
| Tetrabuthylammonium SCHEMBL8449647 | 0.78 | TLR8 (0.37) | TLR8TRPM8 | |
| Tetrabuthylammonium SCHEMBL7902648 | 0.76 | AGTR1 (0.36) | TLR8MAPTSMN1; SMN2LMNATRPM8 | |
| Tetrabuthylammonium SCHEMBL7904701 | 0.76 | TLR8 (0.35) | TLR8TRPM8 | |
| SCHEMBL7896551 | 0.75 | CNR2 (0.36) | TSHRMAPTPIK3CAMTORAR | |
| SCHEMBL7896415 | 0.74 | TLR8 (0.40) | TLR8MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL1207814 | 0.66 | AR (0.58) | MAPTSMN1; SMN2ARLMNAPTPN11 | |
| SCHEMBL7902674 | 0.66 | HRH3 (0.40) | PIK3CAPTPN11PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191152-B1 | CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | EGIS GYÓGYSZERGYAR RT. (HU) | 2001-02-20 | — | — | US | disclosed |