Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 12/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7910744 | 0.94 | ALDH1A1 (0.37) | SPRALDH1A1HPGDCYP3A4CYP2C9 | |
| SCHEMBL7904368 | 0.89 | SPR (0.35) | SPRALDH1A1HPGDCYP3A4CYP2C9 | |
| SCHEMBL10186505 | 0.83 | BCL2 (0.39) | — | |
| SCHEMBL12044372 | 0.83 | TRPM8 (0.36) | SPRNPC1MAPK1 | |
| SCHEMBL7905582 | 0.81 | P2RX7 (0.43) | SPRALDH1A1HPGDPOLBKDM4E | |
| SCHEMBL7907134 | 0.81 | MYC (0.40) | SPRALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL7912508 | 0.81 | USP2 (0.38) | ALDH1A1HPGDCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL12044376 | 0.81 | HCRTR1 (0.33) | SPRCYP3A4LMNA | |
| SCHEMBL14826751 | 0.81 | LHCGR (0.36) | SPRCYP2C19NPC1 | |
| SCHEMBL7905844 | 0.81 | KDM4E (0.53) | SPRALDH1A1HPGDCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010101230-A1 | QUINOXALINE COMPOUNDS | アステラス製薬株式会社 (JP) | 2010-09-10 | — | — | WO | disclosed |