Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNE1 | P15382 | 6/20 | 0.41 |
| ▸ | KCNQ1 | P51787 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | NCF1 | P14598 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7900351 | 0.88 | KCNE1 (0.41) | KCNE1KCNQ1ALDH1A1GAAKDM4E | |
| SCHEMBL7910194 | 0.81 | NCF1 (0.38) | KCNE1KCNQ1ALDH1A1GAAKDM4E | |
| SCHEMBL6602375 | 0.77 | KCNE1 (0.49) | KCNE1KCNQ1ALDH1A1GAAKDM4E | |
| SCHEMBL6600854 | 0.75 | KCNE1 (0.46) | KCNE1KCNQ1ALDH1A1GAAKDM4E | |
| SCHEMBL7909655 | 0.74 | CNR1 (0.40) | ALDH1A1GAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7910113 | 0.72 | ALDH1A1 (0.37) | KCNE1KCNQ1ALDH1A1GAAKDM4E | |
| SCHEMBL6601750 | 0.72 | KCNE1 (0.43) | KCNE1KCNQ1ALDH1A1GAAKDM4E | |
| SCHEMBL7470852 | 0.72 | KCNE1 (0.47) | KCNE1KCNQ1ALDH1A1GAAKDM4E | |
| SCHEMBL6605946 | 0.71 | KCNE1 (0.55) | KCNE1KCNQ1ALDH1A1GAAKDM4E | |
| SCHEMBL7913670 | 0.70 | ATM (0.44) | ALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177449-B1 | CARDIOVASCULAR DISORDERS; ANTIULCER AGENTS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-01-23 | — | — | US | disclosed |