Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.39 |
| ▸ | ITGAL | P20701 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | F3 | P13726 | 2/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.37 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.36 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7909731 | 0.94 | ITGB3 (0.43) | F10ITGB3ITGA2BHTTALDH1A1 | |
| SCHEMBL7900146 | 0.82 | ITGB3 (0.42) | F10ITGB3ITGA2BHTTITGB2 | |
| SCHEMBL7913422 | 0.81 | HTT (0.53) | HTTALDH1A1 | |
| SCHEMBL7909444 | 0.80 | HTT (0.45) | ITGB3HTTALDH1A1ITGA2LMNA | |
| SCHEMBL7900135 | 0.79 | ITGB3 (0.48) | F10ITGB3ITGA2BHTTALDH1A1 | |
| SCHEMBL7909451 | 0.79 | ITGB3 (0.53) | ITGB3ITGA2BHTTITGA2 | |
| SCHEMBL8382626 | 0.77 | EPHX2 (0.48) | ITGB3ITGA2BHTTITGA2LMNA | |
| SCHEMBL7907914 | 0.75 | GAA (0.45) | ITGB3HTTALDH1A1ITGA2LMNA | |
| SCHEMBL9339557 | 0.70 | ITGB3 (0.66) | F10ITGB3ITGA2BITGB2ICAM1 | |
| SCHEMBL8386550 | 0.69 | CASP1 (0.41) | F10ITGB3ITGA2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0608759-B1 | Piperazine derivatives | MERCK PATENT GMBH (DE) | 2001-08-22 | — | — | EP | disclosed |
| EP-0608759-A2 | Piperazinderivatives | MERCK PATENT GmbH (DE) | 1994-08-03 | — | — | EP | disclosed |