Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11930533 | 0.80 | LMNA (0.36) | — | |
| SCHEMBL4194255 | 0.78 | ALDH1A1 (0.30) | — | |
| SCHEMBL25957267 | 0.77 | SMYD2 (0.32) | — | |
| SCHEMBL9697798 | 0.77 | DHFR (0.33) | — | |
| SCHEMBL8170961 | 0.77 | ALDH1A1 (0.38) | — | |
| SCHEMBL2809476 | 0.77 | ALDH1A1 (0.38) | — | |
| SCHEMBL9696668 | 0.77 | DHFR (0.33) | — | |
| SCHEMBL12327949 | 0.76 | MAPK1 (0.33) | — | |
| SCHEMBL2435548 | 0.76 | MAPK1 (0.33) | — | |
| SCHEMBL14256287 | 0.76 | HSD11B1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211184-B1 | TETRAHYDRO-PYRAZINE OR PYRIMIDINE DERIVATIVES; VITRONECTIN RECEPTOR ANTAGONIST; OSTEOPOROSIS; ANTIINFLAMMATORY, ANTITUMOR AGENTS; ANGIOGENESIS AND RESTENOSIS INHIBITORS | MERCK & CO., INC. | 2001-04-03 | — | — | US | disclosed |
| US-5981546-A | Integrin antagonists | MERCK & CO., INC. (US) | 1999-11-09 | — | — | US | disclosed |