Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GLS | O94925 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7598810 | 0.88 | RAB9A (0.56) | L3MBTL1ALDH1A1GAAKMT2ALMNA | |
| SCHEMBL7596229 | 0.86 | KMT2A (0.42) | L3MBTL1ALDH1A1SMN1; SMN2GAAKMT2A | |
| SCHEMBL7593569 | 0.85 | RAB9A (0.54) | ALDH1A1SMN1; SMN2GAAKMT2ALMNA | |
| SCHEMBL7596218 | 0.84 | LMNA (0.43) | L3MBTL1PKMSMN1; SMN2GAAKMT2A | |
| SCHEMBL7916876 | 0.83 | POLB (0.48) | L3MBTL1PKMALDH1A1SMN1; SMN2GAA | |
| SCHEMBL7594895 | 0.82 | RAB9A (0.49) | ALDH1A1GAAKMT2ALMNARAB9A | |
| SCHEMBL7594505 | 0.82 | SMN1; SMN2 (0.41) | ALDH1A1SMN1; SMN2GAAKMT2ALMNA | |
| SCHEMBL7593575 | 0.82 | KDM4C (0.42) | L3MBTL1PKMALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7596958 | 0.82 | KDM4E (0.46) | ALDH1A1GAAKMT2ALMNAKDM4E | |
| SCHEMBL4609558 | 0.81 | ALDH1A1 (0.54) | L3MBTL1PKMALDH1A1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211177-B1 | SIDE EFFECT REDUCTION | CELL PATHWAYS, INC. | 2001-04-03 | — | — | US | disclosed |