Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7594505 | 0.84 | SMN1; SMN2 (0.41) | POLBHCAR3AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL7596229 | 0.83 | KMT2A (0.42) | HCAR3AKR1C3AKR1C2AKR1C1ALDH1A1 | |
| SCHEMBL7910018 | 0.83 | L3MBTL1 (0.49) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7598810 | 0.81 | RAB9A (0.56) | NPC1RAB9AALDH1A1HTTMAPT | |
| SCHEMBL7596218 | 0.81 | LMNA (0.43) | HCAR3AKR1C3AKR1C2AKR1C1RAB9A | |
| SCHEMBL7910012 | 0.80 | FBP1 (0.43) | POLBAKR1C3AKR1C2AKR1C1ALDH1A1 | |
| SCHEMBL7593575 | 0.79 | KDM4C (0.42) | POLBAKR1C3AKR1C2AKR1C1NPC1 | |
| SCHEMBL7596958 | 0.79 | KDM4E (0.46) | POLBHCAR3AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL7593569 | 0.78 | RAB9A (0.54) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7594895 | 0.78 | RAB9A (0.49) | NPC1RAB9AALDH1A1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211177-B1 | SIDE EFFECT REDUCTION | CELL PATHWAYS, INC. | 2001-04-03 | — | — | US | disclosed |