Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNE1 | P15382 | 7/20 | 0.42 |
| ▸ | KCNQ1 | P51787 | 7/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7910522 | 0.88 | KCNE1 (0.43) | KCNE1KCNQ1ALDH1A1PTPN1KCNH2 | |
| SCHEMBL7900359 | 0.88 | KCNE1 (0.41) | KCNE1KCNQ1ALDH1A1GAAKDM4E | |
| SCHEMBL7906977 | 0.85 | CNR2 (0.41) | KCNE1KCNQ1ALDH1A1GAAKDM4E | |
| SCHEMBL7913688 | 0.85 | CTSD (0.36) | KCNE1KCNQ1ALDH1A1GAAKDM4E | |
| SCHEMBL7908101 | 0.81 | ALDH1A1 (0.45) | KCNE1KCNQ1ALDH1A1GAAKDM4E | |
| SCHEMBL7464900 | 0.80 | KCNE1 (0.52) | KCNE1KCNQ1MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL7909736 | 0.80 | ALDH1A1 (0.47) | ALDH1A1GAAKDM4EGLAHPGD | |
| SCHEMBL7900347 | 0.80 | ALDH1A1 (0.39) | KCNE1KCNQ1ALDH1A1GAAKDM4E | |
| SCHEMBL6559231 | 0.77 | KCNE1 (0.52) | KCNE1KCNQ1PTPN1KCNH2SIRT2 | |
| SCHEMBL7910164 | 0.77 | SIRT2 (0.39) | KCNE1KCNQ1ALDH1A1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177449-B1 | CARDIOVASCULAR DISORDERS; ANTIULCER AGENTS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-01-23 | — | — | US | disclosed |