SCHEMBL7910290

SCHEMBL7910290

O=C1NCC=NN1c1cc(Cl)cc(Cl)c1

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.36
CHRM4 P08173 1/20 0.36
ADRB1 P08588 1/20 0.36
CHRM1 P11229 1/20 0.36
CHRM3 P20309 1/20 0.36
NOTUM Q6P988 2/20 0.34
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7917049 0.76 MEN1 (0.34)
SCHEMBL7919391 0.72 NPSR1 (0.38)
SCHEMBL7917757 0.72 FPR2 (0.33)
SCHEMBL7917032 0.72 ENPP2 (0.34)
SCHEMBL7480508 0.72 TYMP (0.35)
SCHEMBL7917711 0.72 MEN1 (0.31) CHRM2CHRM4CHRM1CHRM3TSHR
SCHEMBL7990242 0.71 PRKAB2 (0.33)
SCHEMBL7917047 0.70 CYP3A4 (0.31)
SCHEMBL7917708 0.70 CHEK2 (0.35)
SCHEMBL7919321 0.70 MAPT (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6211178-B1 ANTIPROTOZOA AGENTS FOR COCCIDIOIDES; CYCLIZATION TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2001-04-03 US disclosed
US-5994355-A ANTIPROTOZOA AGENTS, PARASITICIDE; VETERINARY MEDICINE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1999-11-30 US disclosed
EP-0648760-B1 Triazine derivative, production and use thereof TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1999-01-27 EP disclosed
EP-0648760-A2 Triazine derivative, production and use thereof TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1995-04-19 EP disclosed