Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12040079 | 0.95 | TYR (0.47) | TYRPKMHTTALOX5MEN1 | |
| SCHEMBL12040081 | 0.93 | TYR (0.50) | TYRPKMHTTALOX5MEN1 | |
| SCHEMBL11767454 | 0.93 | TYR (0.50) | TYRPKMHTTALOX5MEN1 | |
| SCHEMBL7909326 | 0.89 | ALOX5 (0.46) | PKMHTTALOX5TP53CYP3A4 | |
| SCHEMBL9644638 | 0.83 | PKM (0.64) | TYRPKMHTTALOX5MEN1 | |
| SCHEMBL30449384 | 0.82 | HSD17B1 (0.56) | PKMHTTPOLBHSP90AA1HSP90AB1 | |
| SCHEMBL686132 | 0.82 | HSD17B1 (0.56) | PKMHTTPOLBHSP90AA1HSP90AB1 | |
| SCHEMBL11411118 | 0.80 | TYR (0.63) | TYRHTTALOX5MEN1TP53 | |
| SCHEMBL900912 | 0.79 | RARB (0.51) | TYRTP53MAPTTSHRPOLB | |
| SCHEMBL12040088 | 0.78 | PKM (0.67) | PKMHTTTSHRTDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211328-B1 | IN PRESENCE OF AN ACID | GUN EI CHEMICAL INDUSTRY CO., LTD (JP) | 2001-04-03 | — | — | US | disclosed |
| JP-2000191576-A | ALKENYLPHENOLS OR ISOMER MIXTURE THEREOF | HONSHU CHEM IND CO LTD | 2000-07-11 | — | — | JP | disclosed |