SCHEMBL30449384

SCHEMBL30449384

C=C(C)c1ccc(O)c(CC)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 2/20 0.56
HSP90AA1 P07900 1/20 0.56
HSP90AB1 P08238 1/20 0.56
PKM P14618 1/20 0.52
POLB P06746 1/20 0.49
ESR1 P03372 3/20 0.48
ESR2 Q92731 3/20 0.48
HTT P42858 2/20 0.46
ALDH1A1 P00352 1/20 0.46
HPGD P15428 1/20 0.46
BACE1 P56817 1/20 0.46
JAK2 O60674 1/20 0.43
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38
TRPA1 O75762 1/20 0.38
KDM4E B2RXH2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL686132 1.00 HSD17B1 (0.56) HSD17B1HSP90AA1HSP90AB1PKMPOLB
SCHEMBL7909326 0.85 ALOX5 (0.46) HSD17B1HSP90AA1HSP90AB1PKMPOLB
SCHEMBL10336411 0.84 HSD17B1 (0.43) HSD17B1HSP90AA1HSP90AB1PKMPOLB
SCHEMBL12040088 0.84 PKM (0.67) HSD17B1HSP90AA1HSP90AB1PKMPOLB
SCHEMBL1362391 0.83 HSP90AA1 (0.38) HSD17B1HSP90AA1HSP90AB1PKMPOLB
SCHEMBL10937936 0.83 PKM (0.51) HSD17B1HSP90AA1HSP90AB1PKMPOLB
SCHEMBL10955744 0.82 PKM (0.46) HSD17B1HSP90AA1HSP90AB1PKMPOLB
SCHEMBL7910314 0.82 TYR (0.47) HSD17B1HSP90AA1HSP90AB1PKMPOLB
SCHEMBL385574 0.82 PKM (0.75) HSD17B1HSP90AA1HSP90AB1PKMPOLB
SCHEMBL20262941 0.82 HSD17B1 (0.41) HSD17B1HSP90AA1HSP90AB1PKMPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025132182-A2 POST-EXPOSURE BAKE LESS CHEMICALLY AMPLIFIED PHOTORESIST COMPOSITION MERCK PATENT GMBH (DE) 2025-06-26 WO disclosed
WO-2023085414-A1 POLYCYCLIC AROMATIC HYDROCARBON-BASED PHOTO-CURABLE RESIN COMPOSITION 日産化学株式会社 2023-05-19 WO disclosed