SCHEMBL7910396

SCHEMBL7910396

CCCCC1COC(c2ccc(C#N)cc2)OC1

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 2/20 0.41
TSHR P16473 1/20 0.38
HSD17B10 Q99714 1/20 0.38
CYP2A6 P11509 1/20 0.36
HRH3 Q9Y5N1 3/20 0.34
TBXA2R P21731 2/20 0.33
MGLL Q99685 2/20 0.33
CHRNA10 Q9GZZ6 1/20 0.33
CHRNA9 Q9UGM1 1/20 0.33
TBXAS1 P24557 2/20 0.32
DRD2 P14416 3/20 0.32
DRD3 P35462 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1934266 1.00 GRM2 (0.41) GRM2TSHRHSD17B10CYP2A6HRH3
SCHEMBL10640644 0.96 TSHR (0.44) GRM2TSHRHSD17B10CYP2A6HRH3
SCHEMBL1934965 0.96 GRM2 (0.46) GRM2TSHRHSD17B10CYP2A6HRH3
SCHEMBL4650784 0.96 GRM2 (0.46) GRM2TSHRHSD17B10CYP2A6HRH3
SCHEMBL9556017 0.95 GRM2 (0.39) GRM2TSHRHSD17B10CYP2A6HRH3
SCHEMBL9556014 0.95 GRM2 (0.39) GRM2TSHRHSD17B10CYP2A6HRH3
SCHEMBL11290099 0.94 GRM2 (0.48) GRM2TSHRHSD17B10CYP2A6HRH3
SCHEMBL9362811 0.94 GRM2 (0.48) GRM2TSHRHSD17B10CYP2A6HRH3
SCHEMBL9362814 0.94 GRM2 (0.48) GRM2TSHRHSD17B10CYP2A6HRH3
SCHEMBL8975343 0.94 GRM2 (0.48) GRM2TSHRHSD17B10CYP2A6HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5172256-A Liquid crystal variable color density lens and eye protective devices incorporating the same LIQUID CRYSTAL OPTICS INSTITUTE, INC. 1992-12-15 US claimed
US-4364838-A Liquid crystal mixtures HOFFMANN-LA ROCHE INC. (US) 1982-12-21 US claimed
EP-2511318-B1 METHOD FOR PRODUCING CONJUGATED POLYMER FUJIFILM CORP (JP) 2018-02-21 EP disclosed
US-9449732-B2 Charge transport film, method for producing the same, and light-emitting element and photoelectric conversion element using the same FUJIFILM CORPORATION (JP) 2016-09-20 US disclosed
EP-2511318-A1 METHOD FOR PRODUCING CONJUGATED POLYMER FUJIFILM Corporation (JP) 2012-10-17 EP disclosed
US-20120241326-A1 METHOD OF PREPARING CONJUGATED POLYMER FUJIFILM CORPORATION (JP) 2012-09-27 US disclosed
US-20120238774-A1 CHARGE TRANSPORT FILM, METHOD FOR PRODUCING THE SAME, AND LIGHT-EMITTING ELEMENT AND PHOTOELECTRIC CONVERSION ELEMENT USING THE SAME FUJIFILM CORPORATION (JP) 2012-09-20 US disclosed
US-7335404-B2 Liquid crystal composition for use in bistable liquid crystal devices MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2008-02-26 US disclosed
US-7335404-B2 Liquid crystal composition for use in bistable liquid crystal devices MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2008-02-26 US disclosed
US-7294368-B2 Liquid crystal composition for use in bistable liquid crystal devices MERCK PATENT GMBH (DE) 2007-11-13 US disclosed
US-7294368-B2 Liquid crystal composition for use in bistable liquid crystal devices MERCK PATENT GMBH (DE) 2007-11-13 US disclosed
EP-0074608-A2 Liquid crystal halogen compounds, process for their preparation, dielectric and dectrooptical display element containing them MERCK PATENT GmbH (DE) 1983-03-23 EP disclosed
US-4364838-A Liquid crystal mixtures HOFFMANN-LA ROCHE INC. (US) 1982-12-21 US disclosed
US-4356104-A LIQUID CRYSTALS, ELECTROOPTICAL DISPLAY TIMEX CORPORATION (US) 1982-10-26 US disclosed
US-4335012-A LIQUID CRYSTALS TIMEX CORPORATION (US) 1982-06-15 US disclosed
US-4335012-A LIQUID CRYSTALS TIMEX CORPORATION (US) 1982-06-15 US disclosed
US-4325830-A Three ring dioxane liquid crystalline compounds TIMEX CORPORATION (US) 1982-04-20 US disclosed
US-4322354-A 5-Substituted-2-(4-cyanophenyl)-1,3,-dioxanes TIMEX CORPORATION (US) 1982-03-30 US disclosed
US-4322354-A 5-Substituted-2-(4-cyanophenyl)-1,3,-dioxanes TIMEX CORPORATION (US) 1982-03-30 US disclosed
US-4313878-A LIQUID CRYSTALS TIMEX CORPORATION (US) 1982-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120238774-A1 CHARGE TRANSPORT FILM, METHOD FOR PRODUCING THE SAME, AND LIGHT-EMITTING ELEMENT AND PHOTOELECTRIC CONVERSION ELEMENT USING THE SAME PCTP, CDH1, PLTP GRM2 2589/4885TSHR 4347/4885HSD17B10 3518/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.